Scanning electron micrograph of a HeLa cell undergoing apoptosis
Source: National Institutes of Health (NIH)
Agarose gel of bacterial plasmids
Undergraduate research bench
HIV-infected H9 T-cell
Source: National Institute of Allergy and Infectious Diseases (NIAID)
Welcome to Undergrad in the Lab!
Undergraduate research can be incredibly rewarding, but where do you start and how do you succeed? Navigating this unfamiliar territory is not easy. Here you will find advice on how to find a research position, and how to get the most out of your experience.
Research is to see what everybody else has seen, and to think what nobody else has thought.
— Albert Szent-Györgi (1893-1986) U. S. biochemist.
Even if you're given the option of showing up 'whenever,' schedule your research time because doing so will lead to more advantages than having a spontaneous schedule.
Although there are several advantages to scheduling your lab time, three are:
Research has enough disappointments and surprises that are beyond our control. So, there is no reason that you should ever struggle with low ink or faded labels.
At the bench, you might use a Sharpie as much as a pipette, calculator, or rack. (It's safe to bet that you use one as much as you use microcentrifuge tubes.)
A worn out pen is a seemingly small frustration but it's a hassle you don't need--save your energy for the big problems.
If you don't get what your research supervisor is instructing you to do, ask for clarification until it makes sense and you fully understand the plan. You can't fake your way through your project.
Sometimes it’s unnerving to ask for clarification when you don’t immediately grasp a concept or understand a statement your supervisor or mentor says. He might seem rushed or distracted. You worry that she will think less of you for needing a more detailed explanation.
Hands down, one of the more boring parts of research is the prep work.
Who wants to check if there is ligase, sterile flasks, or enough 5M sodium chloride? In truth, no one does. It’s infinitely more satisfying to get started on the pipetting, mixing, separating, vortexing, or spinning and plan to grab what you need when you need it.
Bring a snack to lab everyday and take the time to eat it. If the lab doesn’t have a designated food area, excuse yourself to the hallway, the lobby, or outside for a few minutes when needed.
If you start your lab after your classes are wrapped up for the day, that snack can make all the difference in your ability to get work done, to focus on a challenging problem, or to let it go when a labmate is irritating.
If your research supervisor, PI, or labmate asks, “How late can you stay at the lab today?” don’t answer with: “Whenever—it doesn’t matter.” Because it does matter.
If you give an open-ended answer, you might find yourself finishing at 4 AM, exhausted and hangry (especially if you already ate your snacks and the vending machine takes your money without giving you food).
Remember, research might not be a 9 to 5 activity for the labmate who’s asking. Always give a time window even if it isn’t precise such as “4:30 to 5:30,” or your absolute cut-off time “7 PM.”